Upregulation of miR-146a-5p in ALS/MND is consistent with Lu et al.'s [65] data suggesting that it binds to the 3′ UTR of TRAF6 mRNA inhibiting both mRNA and protein expression of TRAF6 resulting in a reduction of neuropathic pain. The gene discussed is TRAF6; the disease is amyotrophic lateral sclerosis.