Likewise, Thalidomide was able to reduce macrophages, and lymphocytes count in bleomycin (BLM)-induced pulmonary fibrosis mice model and to suppress IL-6, IL-8, TNF-α, and TGF-β levels in their bronchoalveolar lavage fluid (BALF). This evidence concerns the gene TGFB1 and pulmonary fibrosis.