IFNG and infection: Since CXCL10 secretion is induced by IFNγ treatment in a variety of cell types (CXCL10 is also known as interferon-γ-inducible protein 10 or “IP-10” [44]) and T. gondii IST is known to block IFNγ-induced responses during infection [14, 15], we performed multiple assays with T. gondii strains lacking TgIST.