The present review aims to focus on two other possible consequences than pneumonitis of over-activation of the STING pathway in severe COVID-19, at least in patients with at risk TMEM173 variants, namely: 1-the severe and sometimes lethal Kawasaki diseases (KD) described in some young patients with COVID-19 [20], since several arguments suggest that KD might also be fostered by over-activation of the STING pathway; 2-the frequent resistance of the poor prognosis thrombotic coagulopathy of COVID-19 to thrombo-prophylaxis by heparin or factor Xa inhibitors. The gene discussed is STING1; the disease is Kawasaki disease.