Increased serum levels of adipocytokines, such as leptin, resistin, visfatin, and omentin, were associated with the risk and progression of several obesity‐interrelated cancers,11 we have reported that leptin and relatives may provide a link and potentially promising biomarkers for postmenopausal breast cancer.12, 13. Here, LEP is linked to obesity due to melanocortin 4 receptor deficiency.