SOX2 and central nervous system cancer: The functions of OLIG2 (Ligon et al., 2007; Lu et al., 2016; Mehta et al., 2011), SOX2 (Gangemi et al., 2009; Singh et al., 2017), and NFIA (Glasgow et al., 2017; Lee, Hoxha, & Song, 2017) have previously been reported to be important for regulating the tumorigenic property of glioma cell lines and in glioma mouse models.