Glioblastoma Negative Prognostic (GNP) cells, characterized by enrichment for S100B, SOX2, p-STAT3, and p-STAT5, were associated with decreased overall survival, while Glioblastoma Positive Prognostic (GPP) cells, characterized by co-enrichment of EGFR and CD44 proteins, were associated with longer overall survival. Here, EGFR is linked to glioblastoma.