The MEM protein enrichment values (average and standard deviation) for GNP cells included neural lineage determinants (▲S100B+5±1.6, SOX2+5±1) and phospho-proteins (▲p-STAT3+3±2.1, p-STAT5+2±1.8, p-S6+3±1.4) and identified proteins that were specifically lacking in GNP cells relative to other glioblastoma cell clusters (▼EGFR-2±0.1, GFAP-4±0.7, CD44-4±0) (Figure 1—figure supplement 4). This evidence concerns the gene STAT3 and glioblastoma.