In a Dutch community‐based cohort, increased systolic blood pressure and urinary albumin excretion were associated with increased galectin‐3 levels over time,31 and the Framingham Offspring Study demonstrated that older age, female sex, systolic blood pressure, diabetes mellitus, and body mass index were associated with longitudinal increase in galectin‐3.32 Our study expands this previous work and implicates these potentially modifiable risk factors and pathophysiologic pathways that may contribute to elevated galectin‐3 levels years later in a diverse, community‐based cohort. The gene discussed is ALB; the disease is diabetes mellitus.