Consistently, ARTN and CXC chemokine receptor 4 (CXCR4) were found to be overexpressed in pancreatic cancer tissues, and the migration and invasion of pancreatic cancer cells appears to be promoted by Akt and ERK 1/2/NF‐κB signalling and the stromal cell‐derived factor 1α (SDF‐1α)/CXCR4 axis.97 This evidence concerns the gene CXCL12 and familial pancreatic carcinoma.