We found that both the MΦ1 (CD80+/CD163−) and mixed MΦ1/MΦ2 (CD80+/CD163+) subtypes were significantly decreased in women with endometriosis, while the MΦ2 (CD80−/CD163+) subtype was significantly increased (Fig. 2a, upper panel). Here, CD80 is linked to endometriosis.