Conclusively, multiple logistic regression analyses corroborated AUC CGRP as an independent prognostic factor for outcome in terms of compulsive-obsessive syndrome (OR 5.741, p = 0.018), anxiety (OR 7.748, p = 0.021), depression (OR 2.740, p = 0.005), the supplementary items (OR 2.392, p = 0.004), and the PCS score (OR 0.177, p = 0.001). This evidence concerns the gene CALCA and major depressive disorder.