4-MP injection caused a significant reduction in hepatic steatosis, and the alanine aminotransferase (ALT) or aspartate aminotransferase (AST) levels increased in ethanol-fed mice and correlated with a substantial reduction in the hepatic triglyceride (TG) and cholesterol levels (Fig. 3d,e). The gene discussed is GPT; the disease is Hepatic steatosis.