In comparison, IL-4Rα−/− mice exhibited a suboptimal eosinophilia 2 wk postinfection, which despite being >9-fold significantly impaired compared with WT mice, was nonetheless significantly elevated compared with CCR3−/− animals (0.36 × 106 median level, Kruskal–Wallis one-way ANOVA statistic: 41, p < 0.01 compared with WT or CCR3−/− mice, Dunn multiple comparisons tests; Fig. 2B). This evidence concerns the gene IL4R and Increased total eosinophil count.