The residual eosinophilia was maintained throughout the time course of infection in IL-4Rα−/− mice and was significantly elevated compared with corresponding CCR3−/−-infected animals at 5 wk (p = 0.05) or 12 wk postinfection (p = 0.05; Dunn multiple comparisons tests; Fig. 2B). This evidence concerns the gene IL4R and infection.