We next asked how TAM receptor mutants would fare in two acute liver injury models—a fulminant hepatitis model based on injection of the Jo2 anti-Fas antibody (Lacronique et al, 1996), and an endotoxic shock model precipitated by injection of LPS and D-galactosamine (Car et al, 1994). The gene discussed is FAS; the disease is Fulminant hepatitis.