Interestingly, LMP1-induced NF-κB was found to transcriptionally suppress the expression miR-203 by binding to its promoter region, during which RUNX2 was also activated by Epstein-Barr virus in nasopharyngeal carcinoma [26], which made us shift our focus on the activity of NF-κB in the present study as well. Here, RUNX2 is linked to nasopharyngeal carcinoma.