Nowadays, multidimensional information has been accumulated for AML other than gene mutations and karyotypes, including gene expression, non-coding RNA profile, gene methylation profile, copy number variation, etc. In the present study, we explored regulatory genetic or epigenetic variables of HOXA10, such as methylation of CpG, copy number variation (CNV), lncRNA, microRNA and TF, which affect the gene expression. Here, HOXA10 is linked to acute myeloid leukemia.