Based on Gepia 2.0 (http://gepia2.cancer-pku.cn/), using AML RNAseq dataset of TCGA and Pearson method, LINC00649 is negatively correlated with HOXA1 (p = 0.015), HOXA2 (p = 0.0056), HOXA3 (p = 0.0045), HOXA4 (p = 0.011), HOXA5 (p = 0.0019), HOXA6 (p = 0.0078), HOXA7 (p = 0.00089), HOXA9 (p = 0.002) and HOXA10 (p = 0.0022) significantly. The gene discussed is HOXA1; the disease is acute myeloid leukemia.