In humans, altered expression of AGR2 was described in various adenocarcinomas, such as breast, esophagus, pancreas, lung, and ovary [14] and has been shown to contribute to the acquisition of several cancer cells hallmarks, such as tumor proliferation, anchorage-independent tumor growth, formation of metastasis, and resistance to apoptosis and chemotherapy. This evidence concerns the gene AGR2 and adenocarcinoma.