Complementary to these findings, we show that AGR2 protein significantly contributes to miR-200c-dependent suppression of ZEB1, and in this way, AGR2 together with miR-200c prevent the acquisition of an aggressive phenotype, since decreased ZEB1 expression is tightly associated with the attenuation of migratory and invasive properties of cancer cells [51,52]. Here, AGR2 is linked to cancer.