CD4 and neoplasm: At the same time, tumor size tended to correlate to the percent of TERT2-specific CD4+ T cells responding TERT2 stimulation by production of IL-2, IFN-g/IL-2, and IFN-g/IL-2/TNF-a (p values in the range of 0.058–0.071), whereas no correlation was observed for TERT2-specific CD8+ T cells (Supplementary Figure S11E,F).