SIRT1 and diffuse large B-cell lymphoma: Interestingly, Gene heat map, Gene ontology enrichment analysis (Go analysis) and gene set enrichment analysis (GSEA) revealed that Sirt1 overexpression is strongly correlated with gene signatures associated with Adriamycin-based chemotherapy, suggesting that Sirt1 overexpression may contribute to Adriamycin-resistance in DLBCL.