qRT‐PCR showed that the average expression levels of ENST00000619282, LINC01006 and MIR22HG were significantly higher (Fig. 7A–C) and that of MAPKAPK5‐AS1, LINC01189 and DSCR9 were lower (Fig. 7D–F) in the PBMCs of patients with RA as compared with that in the PBMCs of healthy controls. This evidence concerns the gene MIR22HG and rheumatoid arthritis.