To determine whether the differentially expressed lncRNAs related to inflammation and immunity in the PBMCs of patients with RA were relevant biomarkers for the severity of RA, we performed the Spearman's correlation test to assess the correlation of MIR22HG, DSCR9, LINC01189, MAPKAPK5‐AS1 and ENST00000619282 with clinical indexes and SPP. The gene discussed is MAPKAPK5; the disease is rheumatoid arthritis.