Using molecular functions analysis, we also found that cAMP-dependent protein kinase inhibitor/regulator activity (GO: 0008603, 0004862 and 0004691), cAMP binding (GO:0030552), and G-protein beta/gamma-subunit complex binding (GO: 0031683) were highly enriched in the ADCYs in AML (Figure 5E). This evidence concerns the gene WEE1 and acute myeloid leukemia.