TP53 and neoplasm: While no changes in p‐NF‐κB (p‐P65) levels were detected in tumour‐conditioned BMDM (using mGICPten−/−;p53−/−‐CM and GL261‐CM) (Fig EV4G), we observed a slight increase phosphorylation of NF‐κB (p‐P65) in tumour‐conditioned microglia, an effect enhanced by mTOR inhibition (Figs 6E and EV4F).