CD8A and glioblastoma: Infiltration of CD8+ and CD4+ T cells but not FoxP3+ Treg cells, as observed in our Cx3cr1‐Rheb1Δ/Δ tumours, correlates with long‐term survival in GBM patients (Heimberger et al, 2008; Yang et al, 2010; Abedalthagafi et al, 2018), hence providing the rationale for immunotherapies aimed at modifying the infiltration or immune reactivity of the T‐cell population, such as drugs targeting inhibitory checkpoints.