WFS1 and Hodgkins lymphoma: Table 1 summarizes the clinical features of the 14 WFS1 c.2051C>T (p.A684V) mutations reported to date, which are associated with similarly severe to profound flat HL and age of onset in four ethnic groups worldwide(Chaussenot et al., 2015; Grenier et al., 2016; Kobayashi et al., 2018; Rendtorff et al., 2011; Tessa et al., 2001).