PTPRC and Chronic colitis: After induction of chronic colitis, the increase in neutrophils (19.10% vs 5.91% of CD45+ cells, P = .004) and monocytes (11.80% vs 3.25% of CD45+ cells, P = .004) was more pronounced in RAG−/−γc−/− mice as compared with RAG‐1−/− mice (Figure 6B‐D).