In transcriptional levels, transcription factor regulation, related LncRNA, targeted miRNA, activation and inhibition of G6PC networks were constructed in Figure S2B G6PC mRNA expression showed a negatively relationship with tumour environment purity (r2 = −0.1012, P < 0.0001) and immune purity (r2 = −0.1205, P < 0.0001) in ccRCC (Figure 5B and C). The gene discussed is G6PC1; the disease is nonpapillary renal cell carcinoma.