Classifying by immunohistochemical expression, poor prognostic factors of DLBCL include nongerminal center B-cell (non-GCB) variant, C-MYC and BCL2 double expressor, positive C-MYC, positive BCL2, positive CD5, positive CD30, and positive P53 [15]. The gene discussed is BCL2; the disease is diffuse large B-cell lymphoma.