We conducted immunohistochemical staining for TFE3 in all 50 SFTs and observed malignant peripheral neurilemmoma (n = 10), synovial sarcoma (n = 10), spindle cell lipoma (n = 10), dermatofibrosarcoma protuberans (n = 10), and dedifferentiated liposarcoma (n = 10). This evidence concerns the gene TFE3 and liposarcoma.