Furthermore, the risk of infection is notably greater in individuals with pre-existing medical conditions such as asthma, hypertension, diabetes, etc. It has been hypothesized that angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) may increase the risk of SARS-CoV2 infection and increase the severity of COVID-19 [22]. This evidence concerns the gene ACE and hypertensive disorder.