Likewise, there was no correlation between the infecting pathogen in diabetic foot ulcer with the patient's history of smoking, previous history of diabetic ulcer, type of medication for diabetes (oral or insulin), duration of the ulcer, duration of diabetic disease, or history of amputation (P value = 0.750, 0.268, 0.355, 0.464, 0.253, and 0.509). The gene discussed is INS; the disease is ulcer disease.