A recent study found amyloid beta deposition in a transgenic model of AD (transTgAPPswePS1 mice express the human APP with the Swedish mutations at the β-secretase cleavage site PS1 with increased amyloid beta levels) with a diffuse pattern in the epithelial cells of the cornea as compared to controls, causing cornea epithelial cells degeneration, associated with apoptosis in basal lamina cell [44, 45]. The gene discussed is APP; the disease is Alzheimer disease.