A total of eight WXKL-target genes related to arrhythmia were retrieved from TCMSP, including sodium channel protein type 5 subunit alpha (SCN5A), potassium voltage-gated channel subfamily H member 2 (KCNH2), beta-1 adrenergic receptor (ADRB1), beta-2 adrenergic receptor (ADRB2), alpha-1D adrenergic receptor (ADRA1D), muscarinic acetylcholine receptor M2 (CHRM2), alpha-2A adrenergic receptor (ADRA2A), and gap junction alpha-1 protein (GJA1) (Table 1). The gene discussed is ADRA1D; the disease is cardiac arrhythmia.