PCSK9 and atherosclerosis: Besides, Qu can also affect the expression of LXRα and ABCA1 through the p38-dependent pathway [64], proprotein convertase subtilisin/kexin type 9 (PCSK9) pathway [65], and cholesterol 7 alpha-hydroxylase (CYP7A1) pathway [66] to promote cholesterol efflux and reduce the risk of atherosclerosis.