PTGS2 and nervous system disorder: The therapeutic potential in neurological disorders was also observed in Vaccinium cyanococcus (blueberry) extract, which regulated the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), at the transcriptional level in BV2 microglial cells on lipopolysaccharides (LPS) assault [50].