NFKB1 and skin cancer: Indeed, the canonical NF-κB pathway is one of the most targeted pathways by AEBP1, and the relationship between AEBP1 and the canonical NF-κB pathway is crucial in many types of cancer including, but not limited to, breast cancer, skin cancer, glioblastoma, bladder cancer, gastric cancer, colorectal cancer, ovarian cancer, and leukemia.