Compared with the tumors originating from blank vector-infected MCF-7 cells, tumors originating from anti-RCC2 shRNA-infected cells exhibited a decrease in the average weight from 0.562 g to 0.123 g and in the average tumor volume from 851.8 mm3 to 119.6 mm3 as well as a significant increase in the DWI and ADC values from 0.006 mm2/s to 0.0092 mm2/s. This evidence concerns the gene RCC2 and neoplasm.