Additionally, the subunits eIF3 a, b, c, e, and f have been found as the oncogene overexpressed in several cancers, including nonsmall-cell lung cancer, breast cancer, cervical carcinoma, esophagus squamous-cell carcinoma, gastric carcinoma, and osteosarcoma. The gene discussed is EIF3A; the disease is esophageal squamous cell carcinoma.