In contrast, tumours were formed from as low as 10 injected cells in CYP1B1-VAR cells (p < 10−4 when compared with CYP1B1-WT cells) and, as expected, tumour uptake from ALDH+ cells was significantly higher than from ALDH− cells (p = 0.0015). This evidence concerns the gene CYP1B1 and neoplasm.