Autophagy-related genes were higher in MM-HDN and MGUS than healthy HDN, more than twofold in LC3B (p < 0.001) and p62/SQSTM1 (p = 0.001) expression, while ATG10 (p = 0.02) and GABARAP (p = 0.001) expression was increased only in MM; MGUS-HDN and other autophagy receptors, like OPTN, were not affected (Figure 3D). The gene discussed is OPTN; the disease is Miyoshi myopathy.