VEGFA and glioblastoma: 21.54% cases of de novo GBM and 52.94% of LGG patients showed rare or no expression of VEGFA protein (IHC score 0), 35.38% and 29.42% GBM and LGG respectively were scored as (1) localized and the rest of the patients and all the secondary GBMs had a very high score (2).