Similarly, Bao et al identified an independent prognostic signature for invasive ductal carcinoma30 that consisted of FLT3LG, SPIB, KLRB1, BATF, IGHA1, TIMM8A and QRSL1. In this study, we identified an immune‐related signature comprising SLC10A2, FGF2, CCL28, NDRG1, ESM1, UCN, UTS2 and TRDC for CRC. Here, ESM1 is linked to colorectal carcinoma.