Moreover, glucose levels in the media of HK2-overexpressing KCNQ1OT1-knockdown CRC cells were similar to the media of parental HCT116 cells and significantly higher than in the media of KCNQ1OT1-knockdown CRC cells (Figure 5F, 5G). The gene discussed is KCNQ1OT1; the disease is colorectal carcinoma.