SACK1H and metastatic malignant neoplasm in the lymph nodes: With these cut-off values, FAM83H-N was significantly associated with serum level of CA 19-9, tumor stage, tumor invasion, lymph node metastasis, venous invasion, histologic grade, and the expression of FAM83H-C, SCRIB-N, SCRIB-C, and β-catenin-N (Table 1).