ROC curve indicated that a AST/ALT ratio of 1.155 had maximum Youden index value (Figure 1) (sensitivity = 39.7%, Specificity = 78.4%); thus, patients with AST/ALT ratio < 1.155 had low risk of PCa, while patients with AST/ALT ratio > 1.155 had high risk of incident PCa. The gene discussed is GPT; the disease is posterior cortical atrophy.