MSM is reported to decrease the invasiveness of cells via modulation of vascular endothelial growth factor (VEGF) in breast cancer cells (Lim et al. 2012) as well be tested in combinational therapy with Janus kinase 2 (Jak2) inhibitor in bladder cancer (Joung et al. 2014). The gene discussed is VEGFA; the disease is urinary bladder cancer.