We first examined by western immunoblotting the expression of YBX1 and LC3I/II in in the tumorous and paracancerous tissues from 16 NSCLC patients (Fig. 1a), in the human bronchial epithelial cell line 16HBE, and in 4 NSCLC cell lines (A549, H1299, H460, and HCC827) (Fig. 1b). The gene discussed is YBX1; the disease is non-small cell lung carcinoma.