In addition, we examined the effect of YBX1 overexpress on the expression of tumor-associated protein levels in xenografts by western blotting (Fig. 5e) and IHC analysis (Fig. 5f), and the results showed that YBX1 overexpression considerably increased the p110β, beclin1, LC3I/II proteins expression in the YBX1 overexpression groups compared to the control groups. The gene discussed is BECN1; the disease is neoplasm.