FMR1 and fragile X syndrome: Given the large number of FMRP targets that are associated with synaptic function and the well-described synaptic and network properties that are dysregulated in pre-clinical models of FXS, our present study focuses on assessing the physiological properties of two control (CON1, CON2) and three FXS patient lines (FXS1, FXS2, FXS3) of human cortical neurons derived from induced pluripotent stem cells (iPSCs).