High mRNA expression of OAS1 was significantly associated with worse OS in grade 1 breast cancer (HR = 2.71, 95%CI: 1.11–6.61, p = 0.022), while OAS2 analysis showed the opposite results, as high OAS2 mRNA expression was significantly correlated with a better OS prognosis (HR = 0, 95%CI: 0-lnf, p = 0.0071) (Table 1). The gene discussed is OAS2; the disease is breast cancer.