MUC16 and metastatic malignant neoplasm in the lymph nodes: WFDC2 has also been demonstrated to be a more sensible predictor of lymph node metastasis (sensitivity of 0.82) in relation to MUC16 (0.72) [50] and better in predicting myometrial invasion (AUC of 0.76) than MUC16 (AUC = 0.65) [12].