AKT1 and cancer: Carnosol has anti-cancer, anti-inflammatory, and antioxidant effects mediated by modulating signaling cascades, including effects on molecules that regulate apoptosis (Bax/Bcl2), cell survival and proliferation (AKT/mTOR, MAPK), transcription factors, NF-κB, STAT3-6, and steroid androgen and estrogen receptors [199].