In practice, definitions of a response to chemotherapy can be envisioned from several perspectives, both clinical complete remission (with negative imaging scans and normalization of alpha-fetoprotein (AFP) and human chorionic gonadotropin (HCG) serum levels), surgical complete remission (implying the absence of residual macroscopic disease after the surgical procedure), or pathological complete remission (allowing the presence of necrosis/fibrosis or mature teratoma but no evidence of a nonteratoma viable disease), all of which bring distinct inputs to clinical decision-making [25]. Here, AFP is linked to teratoma.